Anthracycline and Peripartum Cardiomyopathies
نویسندگان
چکیده
منابع مشابه
Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies.
Background Peripartum cardiomyopathy shares some clinical features with idiopathic dilated cardiomyopathy, a disorder caused by mutations in more than 40 genes, including TTN, which encodes the sarcomere protein titin. Methods In 172 women with peripartum cardiomyopathy, we sequenced 43 genes with variants that have been associated with dilated cardiomyopathy. We compared the prevalence of diff...
متن کاملShared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies
RESULTS We identified 26 distinct, rare truncating variants in eight genes among women with peripartum cardiomyopathy. The prevalence of truncating variants (26 in 172 [15%]) was significantly higher than that in a reference population of 60,706 persons (4.7%, P = 1.3×10−7) but was similar to that in a cohort of patients with dilated cardiomyopathy (55 of 332 patients [17%], P = 0.81). Two thir...
متن کاملRight ventricular systolic function in peripartum and dilated cardiomyopathies.
AIMS Right ventricular (RV) systolic function of peripartum cardiomyopathy (PPCM) has not previously been well described and compared with that of dilated cardiomyopathy (DCM). The aim of the present study was therefore to assess and compare RV systolic function between PPCM and idiopathic DCM, using tricuspid annular plane systolic excursion (TAPSE). METHODS AND RESULTS The study was cross s...
متن کاملCorrigendum: Mutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies
Cardiomyopathy is an important cause of heart failure in Sub-Saharan Africa, accounting for up to 30% of adult heart failure hospitalisations. This high prevalence poses a challenge in societies without access to resources and interventions essential for disease management. Over 80 genes have been implicated as a cause of cardiomyopathy. Mutations in the phospholamban (PLN) gene are associated ...
متن کاملMutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies
Citation Fish, Maryam, Gasnat Shaboodien, Sarah Kraus, Karen Sliwa, Christine E. Seidman, Michael A. Burke, Lia Crotti, Peter J. Schwartz, and Bongani M. Mayosi. 2016. “Mutation analysis of the phospholamban gene in 315 South Africans with dilated, hypertrophic, peripartum and arrhythmogenic right ventricular cardiomyopathies.” Scientific Reports 6 (1): 22235. doi:10.1038/srep22235. http://dx.d...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2019
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.119.313577